Runaway electrons (REs) are a concern for tokamak fusion reactors from discharge startup to termination. A sudden localized loss of a multi-megaampere RE beam can inflict severe damage to the first wall. Should a disruption occur, the existence of a RE seed may play a significant role in the formation of a RE beam and the magnitude of its current. The application of central electron cyclotron resonance heating (ECRH) in the Tokamak à Configuration Variable (TCV) reduces an existing RE seed population by up to three orders of magnitude within only a few hundred milliseconds. Applying ECRH can also prevent the formation of a post-disruption RE beam where it would otherwise be expected. The RE expulsion rate and consequent RE current reduction are found to increase with applied ECRH power. A simple 0-D model for the evolution of the RE population is presented that explains how the effective ECRH-induced RE expulsion results from the combined effects of reduced avalanche RE generation and enhanced RE transport.